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Inducible ablation of CD11c⁺ cells to determine their role in skin wound repair

Li, Z; Lamb, R; Coles, MC; Bennett, CL; Ambler, CA; (2021) Inducible ablation of CD11c⁺ cells to determine their role in skin wound repair. Immunology , 163 (1) pp. 105-111. 10.1111/imm.13312. Green open access

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Abstract

Wound healing in healthy skin requires a complex interplay between immune and non‐immune cells. In addition to their roles in infection control and cell debridement, leukocytes secrete factors to orchestrate the timing of the repair process via cross‐talk with epithelia. This critical role in wound timing is vital as failure to induce wound closure leads to debilitating chronic wounds susceptible to further infection and patient sepsis.

Type: Article
Title: Inducible ablation of CD11c⁺ cells to determine their role in skin wound repair
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1111/imm.13312
Publisher version: https://doi.org/10.1111/imm.13312
Language: English
Additional information: This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Keywords: CD11c, Dendritic cells, Langerhans cells, skin, wound repair
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Haematology
URI: https://discovery-pp.ucl.ac.uk/id/eprint/10120384
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