Saso, S;
Clancy, NT;
Jones, BP;
Bracewell-Milnes, T;
Al-Memar, M;
Cannon, EM;
Ahluwalia, S;
... Ghaem-Maghami, S; + view all
(2018)
Use of biomedical photonics in gynecological surgery: a uterine transplantation model.
Future Science OA
, 4
(4)
, Article FSO286. 10.4155/fsoa-2017-0129.
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Abstract
Aim: Uterine transplantation (UTx) has been proposed as a treatment for permanent absolute uterine factor infertility. The study aims were to compare pulse oximetry and multispectral imaging (MSI), for intraoperative tracking of uterine oxygen saturation in animal UTx models (rabbit and sheep). Results/methodology: Imaging results confirmed the re-establishment of adequate perfusion in the transplanted organ after surgery. Comparison of oxygen saturation values between the pre-UTx donor and post-UTx recipient, and pre-UTx and post-UTx recipient reveals a statistically significant decrease in saturation levels post-UTx. Conclusion: The use of MSI is the first case in gynecology and has demonstrated promise of possible future human use. MSI technique has advantages over pulse oximetry – it provides spatial information in a real-time, noncontact manner.
| Type: | Article |
|---|---|
| Title: | Use of biomedical photonics in gynecological surgery: a uterine transplantation model |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.4155/fsoa-2017-0129 |
| Publisher version: | https://doi.org/10.4155/fsoa-2017-0129 |
| Language: | English |
| Additional information: | This work is licensed under the Creative Commons Attribution 4.0 License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
| Keywords: | optical imaging, oxygen saturation, surgical imaging, tissue perfusion, uterine transplantation |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10120496 |
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