Ilo, KC;
Aboelmagd, K;
Hothi, HS;
Asaad, A;
Skinner, JA;
Hart, AJ;
(2019)
Does modularity of metal-on-metal hip implants increase cobalt: chromium ratio?
HIP International
, 31
(1)
pp. 109-114.
10.1177/1120700019873637.
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Abstract
Background: Blood metal ion levels are used in the surveillance of metal-on-metal (MoM) hip implants. Modular implants contain an extra source of metal debris that may affect the ratio of metal ions in the blood. Methods: This was a retrospective study of 503 patients with hip replacements made by a single manufacturer (Smith & Nephew, Warwick, UK) with the same bearing surface. There were 54 total hip arthroplasties, 35 Birmingham Mid-Head Resections and 414 hip resurfacings. Whole blood metal ion levels and their ratios were analysed to investigate the effect of a modular junction. Results: The cobalt:chromium ratios were greater in the total hip arthroplasty group (mean 2.3:1) when compared to the resurfacings group (mean 1.3:1, p = <0.05) and Birmingham Mid-Head Resection group (mean 1.1:1, p = 0.11). Conclusions: This study demonstrated a trend for a higher cobalt:chromium ratio in patients with MoM total hip replacement that may be due to metal debris from the modular stem-head junction. Further work is required to correlate clinical data with retrieval analysis to confirm the effect of taper material loss on the cobalt:chromium ratio.
Type: | Article |
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Title: | Does modularity of metal-on-metal hip implants increase cobalt: chromium ratio? |
Open access status: | An open access version is available from UCL Discovery |
DOI: | 10.1177/1120700019873637 |
Publisher version: | http://dx.doi.org/10.1177/1120700019873637 |
Language: | English |
Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
Keywords: | Arthroplasty, blood metal ions, hip, modular, LOCAL TISSUE REACTION, ION LEVELS, CORROSION, TAPER, ARTHROPLASTY, BLOOD, PROSTHESES, REVISION, JUNCTION |
UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Ortho and MSK Science |
URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10124458 |
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