Ray, JC;
Hutton, EJ;
Matharu, M;
(2021)
OnabotulinumtoxinA in Migraine: A Review of the Literature and Factors Associated with Efficacy.
Journal of Clinic Medicine
, 10
(13)
, Article 2898. 10.3390/jcm10132898.
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Abstract
The efficacy of onabotulinumtoxinA (OnaB-A) as a preventative treatment for chronic migraine, emerging fortuitously from clinical observation is now supported by class one evidence and over two decades of real-world clinical data. There is still limited ability to predict a clinically meaningful response to OnaB-A for individual patients, however. This review summarises briefly the proposed mechanism of OnaB-A in chronic migraine, the literature of predictors of clinical response, and recent developments in the field.
Type: | Article |
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Title: | OnabotulinumtoxinA in Migraine: A Review of the Literature and Factors Associated with Efficacy |
Location: | Switzerland |
Open access status: | An open access version is available from UCL Discovery |
DOI: | 10.3390/jcm10132898 |
Publisher version: | http://dx.doi.org/10.3390/jcm10132898 |
Language: | English |
Additional information: | This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
Keywords: | botulinum toxin, migraine, predictors of efficacy |
UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Brain Repair and Rehabilitation |
URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10130678 |
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