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Three-dimensional versus two-dimensional postmortem ultrasound: feasibility in perinatal death investigation

Shelmerdine, SC; Sebire, NJ; Arthurs, OJ; (2021) Three-dimensional versus two-dimensional postmortem ultrasound: feasibility in perinatal death investigation. Pediatric Radiology , 51 (7) pp. 1259-1266. 10.1007/s00247-020-04934-4. Green open access

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Abstract

Three- and four-dimensional US techniques in antenatal screening are commonplace, but they are not routinely used for perinatal postmortem US. In this technical innovation, we performed both two-dimensional (2-D) and three-dimensional (3-D) postmortem US on 11 foetuses (mean gestation: 23 weeks; range: 15–32 weeks) to determine whether there was any benefit in 3-D over conventional 2-D methods. In one case of osteogenesis imperfecta, both 2-D and 3-D US images were non-diagnostic because of small foetal size. Of the remaining 10 foetuses, 7 were normal at imaging and autopsy, and 3 had abnormalities detected on both 2-D and 3-D US. There were no false-positive diagnoses by 2-D or 3-D US. Whilst 3-D postmortem US was a feasible technique, it did not provide additional information over 2-D US. Routine 3-D postmortem US cannot therefore be routinely recommended based on our findings.

Type: Article
Title: Three-dimensional versus two-dimensional postmortem ultrasound: feasibility in perinatal death investigation
Open access status: An open access version is available from UCL Discovery
DOI: 10.1007/s00247-020-04934-4
Publisher version: https://doi.org/10.1007/s00247-020-04934-4
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Autopsy, Foetus, Pathology, Perinatal, Postmortem, Three-dimensional ultrasound, Ultrasound
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Neurosciences Dept
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Population, Policy and Practice Dept
URI: https://discovery-pp.ucl.ac.uk/id/eprint/10131363
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