Hol, JA;
Jewell, R;
Chowdhury, T;
Duncan, C;
Nakata, K;
Oue, T;
Gauthier-Villars, M;
... Jongmans, MCJ; + view all
(2021)
Wilms tumour surveillance in at-risk children: Literature review and recommendations from the SIOP-Europe Host Genome Working Group and SIOP Renal Tumour Study Group.
European Journal of Cancer
, 153
pp. 51-63.
10.1016/j.ejca.2021.05.014.
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Abstract
Since previous consensus-based Wilms tumour (WT) surveillance guidelines were published, novel genes and syndromes associated with WT risk have been identified, and diagnostic molecular tests for previously known syndromes have improved. In view of this, the International Society of Pediatric Oncology (SIOP)-Europe Host Genome Working Group and SIOP Renal Tumour Study Group hereby present updated WT surveillance guidelines after an extensive literature review and international consensus meetings. These guidelines are for use by clinical geneticists, pediatricians, pediatric oncologists and radiologists involved in the care of children at risk of WT. Additionally, we emphasise the need to register all patients with a cancer predisposition syndrome in national or international databases, to enable the development of better tumour risk estimates and tumour surveillance programs in the future.
| Type: | Article |
|---|---|
| Title: | Wilms tumour surveillance in at-risk children: Literature review and recommendations from the SIOP-Europe Host Genome Working Group and SIOP Renal Tumour Study Group. |
| Location: | England |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.ejca.2021.05.014 |
| Publisher version: | https://doi.org/10.1016/j.ejca.2021.05.014 |
| Language: | English |
| Additional information: | Crown Copyright © 2021 Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).Available online atwww.sciencedirect.comScienceDirectjournalhomepage:www.ejcancer.comEuropean Journal of Cancer 153 (2021) 51e63 |
| Keywords: | Cancer predisposition syndrome, Nephroblastoma, Overgrowth syndrome, Surveillance, WT1, Wilms tumour |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Biology and Cancer Dept |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10131454 |
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