Goddings, AL;
Roalf, D;
Lebel, C;
Tamnes, CK;
(2021)
Development of white matter microstructure and executive functions during childhood and adolescence: a review of diffusion MRI studies.
Developmental Cognitive Neuroscience
, 51
, Article 101008. 10.1016/j.dcn.2021.101008.
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Abstract
Diffusion magnetic resonance imaging (dMRI) provides indirect measures of white matter microstructure that can be used to make inferences about structural connectivity within the brain. Over the last decade, a growing literature of cross-sectional and longitudinal studies have documented relationships between dMRI indices and cognitive development. In this review, we provide a brief overview of dMRI methods and how they can be used to study white matter and connectivity and review the extant literature examining the links between dMRI indices and executive functions during development. We explore the links between white matter microstructure and specific executive functions: inhibition, working memory and cognitive shifting, as well as performance on complex executive function tasks. Concordance in findings across studies are highlighted, and potential explanations for discrepancies between results, together with challenges with using dMRI in child and adolescent populations, are discussed. Finally, we explore future directions that are necessary to better understand the links between child and adolescent development of structural connectivity of the brain and executive functions.
| Type: | Article |
|---|---|
| Title: | Development of white matter microstructure and executive functions during childhood and adolescence: a review of diffusion MRI studies |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.dcn.2021.101008 |
| Publisher version: | https://doi.org/10.1016/j.dcn.2021.101008 |
| Language: | English |
| Additional information: | © 2021 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/) |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Population, Policy and Practice Dept |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10134383 |
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