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The role of sleep disorders in the onset, persistence, and remission of psychotic experiences in children

Reeve, Sarah; (2021) The role of sleep disorders in the onset, persistence, and remission of psychotic experiences in children. Doctoral thesis (D.Clin.Psy), UCL (University College London). Green open access

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Abstract

An association between sleep and psychotic symptoms is increasingly apparent and offers opportunities for intervention and understanding of the etiology of psychosis. This thesis explores the link between sleep and psychotic symptoms in middle childhood and preadolescence, and is presented in three parts. Part 1 is a conceptual review of the association between nightmares and hallucinations in middle childhood. The high prevalence of nightmares and hallucinations within middle childhood is framed within the context of socio-cognitive and neural developmental changes in this period, and links are made with mechanisms relevant to both phenomena including trauma, emotion regulation, and anxiety. Part 2 utilises a large dataset from the ongoing ABCD cohort study to investigate the relationships between sleep and distressing psychotic symptoms in 10-11 year-olds over a one year observation period. Sleep problems are found to significantly predict later distressing psychotic symptoms, and particularly strongly predict persistence of distressing psychotic symptoms across the study period. Nightmares are analysed separately and are also significantly associated with psychotic experiences, but do not significantly predict psychotic experiences above other sleep disorders. The results nevertheless support a role of sleep problems in predicting persistence of distressing psychotic experiences., for which implications are discussed. Part 3 is a critical appraisal of both the open science methodology applied in Part 2 and the challenges still to be faced in establishing sleep as a therapeutic target in mental health.

Type: Thesis (Doctoral)
Qualification: D.Clin.Psy
Title: The role of sleep disorders in the onset, persistence, and remission of psychotic experiences in children
Event: UCL (University College London)
Open access status: An open access version is available from UCL Discovery
Language: English
Additional information: Copyright © The Author [year]. Original content in this thesis is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) Licence (https://creativecommons.org/licenses/by-nc/4.0/). Any third-party copyright material present remains the property of its respective owner(s) and is licensed under its existing terms. Access may initially be restricted at the author’s request.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences > Clinical, Edu and Hlth Psychology
URI: https://discovery-pp.ucl.ac.uk/id/eprint/10134910
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