Narayan, A;
Rahi, J;
Solebo, A;
(2021)
Temporal Trends in Childhood Uveitis: Using Administrative Health Data to Investigate the Impact of Health Policy and Clinical Practice.
Ocular Immunology and Inflammation
10.1080/09273948.2021.1976215.
(In press).
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Abstract
Background: We describe an investigation of temporal trends in the incidence of childhood uveitis-related hospital admissions, hospitalization being a robust indicator of disease severity. Methods: A population-based retrospective study using a hospitalization database, the Hospital Episode Statistics (HES) dataset, capturing data on care between 2013 and 2020. Primary outcomes were rates of pediatric hospital admissions for uveitis-related disorders. Results: During the study period, there were 3,258 reported uveitis-related hospital admissions of children aged 0 to 14 years, comprising 19% of all-age uveitis-related admissions. Anterior uveitis was the most common diagnosis. The annual incidence of childhood uveitis-related hospitalizations declined year on year from a peak incidence of 5.4 per 100,000 children (95% confidence interval 5.0–5.9) in 2015–2016 to 3.3 per 100,000 (95% CI 3.0–3.6) in 2019–2020. Over the same period, the national incidence of juvenile arthropathy-related admissions stayed stable. Conclusion: The decline in admissions nationally may reflect reduced incidence of uveitis complications with increasing use of immunosuppressive therapies.
| Type: | Article |
|---|---|
| Title: | Temporal Trends in Childhood Uveitis: Using Administrative Health Data to Investigate the Impact of Health Policy and Clinical Practice |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1080/09273948.2021.1976215 |
| Publisher version: | https://doi.org/10.1080/09273948.2021.1976215 |
| Language: | English |
| Additional information: | © 2021 The Author(s). Published with license by Taylor & Francis Group, LLC. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way. |
| Keywords: | Uveitis, child, epidemiology, outcome assessment, health care |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Population, Policy and Practice Dept |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10135042 |
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