Jones, D;
di Martino, E;
Bradley, S;
Essang, B;
Hemphill, S;
Renzi, C;
Wright, J;
... Neal, R; + view all
(2022)
Factors affecting the decision to investigate older adults with potential cancer symptoms: a systematic review.
British Journal of General Practice
, 72
(714)
e1-e10.
10.3399/BJGP.2021.0257.
Preview |
Text
Renzi_e1.full.pdf Download (159kB) | Preview |
Abstract
Background: Older age and frailty increase the risk of morbidity and mortality from cancer surgery and intolerance of chemotherapy and radiotherapy. The effect of old age on diagnostic intervals is unknown; however, older adults need a balanced approach to the diagnosis and management of cancer symptoms, considering the benefits of early diagnosis, patient preferences, and the likely prognosis of a cancer. Aim: To examine the association between older age and diagnostic processes for cancer, and the specific factors that affect diagnosis. Design and setting: A systematic literature review. Method: Electronic databases were searched for studies of patients aged >65 years presenting with cancer symptoms to primary care considering diagnostic decisions. Studies were analysed using thematic synthesis and according to the Synthesis Without Meta-analysis guidelines. Results: Data from 54 studies with 230 729 participants were included. The majority of studies suggested an association between increasing age and prolonged diagnostic interval or deferral of a decision to investigate cancer symptoms. Thematic synthesis highlighted three important factors that resulted in uncertainty in decisions involving older adults: presence of frailty, comorbidities, and cognitive impairment. Data suggested patients wished to be involved in decision making, but the presence of cognitive impairment and the need for additional time within a consultation were significant barriers. Conclusion: This systematic review has highlighted uncertainty in the management of older adults with cancer symptoms. Patients and their family wished to be involved in these decisions. Given the uncertainty regarding optimum management of this group of patients, a shared decision-making approach is important.
| Type: | Article |
|---|---|
| Title: | Factors affecting the decision to investigate older adults with potential cancer symptoms: a systematic review |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.3399/BJGP.2021.0257 |
| Publisher version: | https://doi.org/10.3399/BJGP.2021.0257 |
| Language: | English |
| Additional information: | © The Authors http://creativecommons.org/licenses/by/4.0/ This article is Open Access: CC BY 4.0 licence (http://creativecommons.org/licences/by/4.0/). |
| Keywords: | cancer, decision making, shared, early detection of cancer, frail elderly, primary health care, systematic review |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Behavioural Science and Health |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10136094 |
Archive Staff Only
 |
View Item |
