Chio, W-IK;
Xie, H;
Zhang, Y;
Lan, Y;
Lee, T-C;
(2021)
SERS biosensors based on cucurbituril-mediated nanoaggregates for wastewater-based epidemiology.
TrAC Trends in Analytical Chemistry
, Article 116485. 10.1016/j.trac.2021.116485.
(In press).
Preview |
Text
Lan_SERS biosensors based on cucurbituril-mediated nanoaggregates for wastewater-based epidemiology_Pre-proof.pdf - Accepted Version Download (1MB) | Preview |
Abstract
Hierarchical self-assembly of nanoparticles (NPs) mediated by macrocyclic molecules, cucurbiturils (CBs), provides a facile method to fabricate surface-enhanced Raman spectroscopy (SERS) sensors for potential applications in biosensing and environmental monitoring. In contrast to conventional techniques for wastewater-based epidemiology (WBE), CB-NP SERS sensors offer great opportunities for on-site quantification of trace chemical and biological markers due to its high sensitivity, selectivity, reproducibility, multiplexing capability and tolerance against contamination. The working principles of the CB-Au NP nanocomposites including fabrication, sensing mechanisms and structure-property relationships are explained while the design guidelines and selected examples of CB-Au NP SERS sensors are discussed. The review concludes by highlighting recent advances in this area and exploring opportunities in the context of WBE.
| Type: | Article |
|---|---|
| Title: | SERS biosensors based on cucurbituril-mediated nanoaggregates for wastewater-based epidemiology |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.trac.2021.116485 |
| Publisher version: | https://doi.org/10.1016/j.trac.2021.116485 |
| Language: | English |
| Additional information: | © 2021 The Authors. This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/) |
| Keywords: | Wastewater-based epidemiology; surface-enhanced Raman spectroscopy; biosensing; environmental monitoring; cucurbituril; gold nanoparticles; self-assembly; host-guest complexation; nanocomposites |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Chemical Engineering UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > MAPS Faculty Office UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > MAPS Faculty Office > Institute for Materials Discovery |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10138925 |
Archive Staff Only
 |
View Item |
