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T-cell responses to SARS-CoV-2 in healthy controls and primary immunodeficiency patients

Awuah, Arnold; Zamani, Ava; Tahami, Fariba; Davis, Mark; Grandjean, Louis; Buckland, Matthew; Gilmour, Kimberly; (2022) T-cell responses to SARS-CoV-2 in healthy controls and primary immunodeficiency patients. Clinical and Experimental Immunology , 207 (3) pp. 336-339. 10.1093/cei/uxac001. Green open access

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Abstract

Understanding the T cell response to SARS-CoV-2 is key in patients who lack antibody production. We demonstrate the applicability of a functional assay to measure the T cell response in a cohort of patients with immunodeficiency.

Type: Article
Title: T-cell responses to SARS-CoV-2 in healthy controls and primary immunodeficiency patients
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1093/cei/uxac001
Publisher version: https://doi.org/10.1093/cei/uxac001
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions.
Keywords: Antibody Deficiency, COVID19, Immune Deficiency, Immune Response, Proliferation, SARS-COV2, T-cell
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Infection, Immunity and Inflammation Dept
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
URI: https://discovery-pp.ucl.ac.uk/id/eprint/10142806
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