Nakamura, Carina Akemi;
Mitchell, Paul M;
Peters, Tim J;
Moreno-Agostino, Darío;
Araya, Ricardo;
Scazufca, Marcia;
Hollingworth, William;
(2022)
A validation study of the EQ-5D-5L and ICECAP-O among older individuals with depressive symptoms in Brazil.
Value in Health Regional Issues
, 30
pp. 91-99.
10.1016/j.vhri.2021.11.005.
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Abstract
Objectives: This study aimed to assess the known-groups validity of the EQ-5D-5L and the ICECAP-O, two outcome measures used in economic evaluation, among older adults with depressive symptoms in socio-economically deprived areas of Brazil. We also explored the role of education and income on responses to these measures. Methods: This cross-sectional study used baseline data from PROACTIVE, a cluster randomised controlled trial to evaluate a psychosocial intervention for late life depression among older adults. Participants aged 60 years or over with a Patient Health Questionnaire (PHQ-9) score≥10 were recruited from 20 primary healthcare clinics. Ordered logistic regression models assessed the association between depression severity, income and education and dimension level responses on the EQ-5D-5L and ICECAP-O. Multivariable regression models investigated the ability of EQ-5D-5L and ICECAP-O scores to discriminate between depression severity levels and other characteristics, including education level and household income. Results: 715 participants were included in the study. Depression severity was associated with all EQ-5D-5L and ICECAP-O dimensions, except the ICECAP-O enjoyment attribute. Household income, on the other hand, was only associated with the ICECAP-O security attribute. Higher severity of depressive symptoms (PHQ-9 scores) were also strongly associated with lower (i.e. worse) scores on both measures in all models. Education level and household income showed no association with either EQ-5D-5L or ICECAP-O scores. Conclusions: This is the first study that investigated the validity of these two measures among older adults in Brazil. Both EQ-5D-5L and ICECAP-O showed evidence of validity in differentiating depressive symptom severity.
| Type: | Article |
|---|---|
| Title: | A validation study of the EQ-5D-5L and ICECAP-O among older individuals with depressive symptoms in Brazil |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.vhri.2021.11.005 |
| Publisher version: | https://doi.org/10.1016/j.vhri.2021.11.005 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions. |
| UCL classification: | UCL > Provost and Vice Provost Offices > School of Education > UCL Institute of Education UCL > Provost and Vice Provost Offices > School of Education > UCL Institute of Education > IOE - Social Research Institute UCL > Provost and Vice Provost Offices > School of Education UCL |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10143627 |
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