Kondarage, AI;
Gayani, B;
Poologasundarampillai, G;
Nommeots-Nomm, A;
Lee, PD;
Lalitharatne, TD;
Nanayakkara, ND;
... Karunaratne, A; + view all
(2021)
Detection and Tracking Volumes of Interest in 3D Printed Tissue Engineering Scaffolds using 4D Imaging Modalities.
In:
Proceedings of the 2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC).
(pp. pp. 1230-1233).
IEEE: Mexico.
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EMBC2021_Detection_and_Tracking_Volumes_of_Interest_in_3D_printed_scaffolds.pdf - Accepted Version Download (2MB) | Preview |
Abstract
Additive manufacturing (AM) platforms allow the production of patient tissue engineering scaffolds with desirable architectures. Although AM platforms offer exceptional control on architecture, post-processing methods such as sintering and freeze-drying often deform the printed scaffold structure. In-situ 4D imaging can be used to analyze changes that occur during post-processing. Visualization and analysis of changes in selected volumes of interests (VOIs) over time are essential to understand the underlining mechanisms of scaffold deformations. Yet, automated detection and tracking of VOIs in the 3D printed scaffold over time using 4D image data is currently an unsolved image processing task. This paper proposes a new image processing technique to segment, detect and track volumes of interest in 3D printed tissue engineering scaffolds. The method is validated using a 4D synchrotron sourced microCT image data captured during the sintering of bioactive glass scaffolds in-situ. The proposed method will contribute to the development of scaffolds with controllable designs and optimum properties for the development of patient-specific scaffolds.
| Type: | Proceedings paper |
|---|---|
| Title: | Detection and Tracking Volumes of Interest in 3D Printed Tissue Engineering Scaffolds using 4D Imaging Modalities |
| Event: | 2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC) |
| Location: | United States |
| Dates: | 1 Nov 2021 - 5 Nov 2021 |
| ISBN-13: | 9781728111797 |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1109/EMBC46164.2021.9630587 |
| Publisher version: | https://doi.org/10.1109/EMBC46164.2021.9630587 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | Humans, Printing, Three-Dimensional, Tissue Engineering, Tissue Scaffolds, X-Ray Microtomography |
| UCL classification: | UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Mechanical Engineering UCL > Provost and Vice Provost Offices > UCL BEAMS UCL |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10144498 |
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