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Intussusception and COVID-19 in Infants: Evidence for an Etiopathologic Correlation

Scottoni, Federico; Giobbe, Giovanni Giuseppe; Zambaiti, Elisa; Khalaf, Sahira; Sebire, Neil J; Curry, Joe; De Coppi, Paolo; (2022) Intussusception and COVID-19 in Infants: Evidence for an Etiopathologic Correlation. Pediatrics , 149 (6) , Article e2021054644. 10.1542/peds.2021-054644. Green open access

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Abstract

Non-respiratory conditions related to SARS-CoV-2 infections have been largely described. Ileocolic intussusception has been reported in association with SARS-CoV-2 infection in ten children, raising the possibility of an etiopathologic role for the virus, but none of these cases documented tissue pathology that would have supported SARS-CoV-2 intestinal inflammation. We report two cases of intussusception in patients with SARS-CoV-2 infection who were treated at different pediatric tertiary centers in Europe and provide evidence of the presence of the virus in mesenteric and intestinal tissues of the patients.

Type: Article
Title: Intussusception and COVID-19 in Infants: Evidence for an Etiopathologic Correlation
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1542/peds.2021-054644
Publisher version: https://doi.org/10.1542/peds.2021-054644
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions.
Keywords: covid-19, intussusception, sars-cov-2, severe acute respiratory syndrome, ileocolic intussusception, intestines, inflammation
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Population, Policy and Practice Dept
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
URI: https://discovery-pp.ucl.ac.uk/id/eprint/10145963
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