Godakumara, Kasun;
Dissanayake, Keerthie;
Hasan, Mohammad Mehedi;
Kodithuwakku, Suranga P;
Fazeli, Alireza;
(2022)
Role of extracellular vesicles in intercellular communication during reproduction.
Reproduction in Domestic Animals: physiology, pathology, biotechnology
10.1111/rda.14205.
(In press).
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Abstract
The mammalian reproduction is a process of controlled cellular growth and development regulated by constant communication between the gametes, the subsequent embryo, and the maternal system. Extracellular vesicles (EV) are involved in these communications to a significant degree from the gamete production and maturation to fertilization, embryo development and implantation. They regulate the cellular physiology and the immune reaction to bring about a favourable environment for a successful pregnancy. Deciphering the mechanisms employed in EV mediated embryo maternal communication could improve our knowledge in mammalian reproduction and increase the efficiency of animal breeding.
| Type: | Article |
|---|---|
| Title: | Role of extracellular vesicles in intercellular communication during reproduction |
| Location: | Germany |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1111/rda.14205 |
| Publisher version: | https://doi.org/10.1111/rda.14205 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | Embryo-maternal communication, Extracellular vesicles, Immune regulation, Intercellular signalling, Maternal recognition of pregnancy |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL EGA Institute for Womens Health > Maternal and Fetal Medicine UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL EGA Institute for Womens Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10152503 |
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