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Proportion of suicides in Denmark attributable to bereavement by the suicide of a first-degree relative or partner: nested case-control study

Pitman, Alexandra; McDonald, Keltie; Logeswaran, Yanakan; Lewis, Gemma; Cerel, Julie; Erlangsen, Annette; (2022) Proportion of suicides in Denmark attributable to bereavement by the suicide of a first-degree relative or partner: nested case-control study. Acta Psychiatrica Scandinavica 10.1111/acps.13493. Green open access

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Abstract

Objective: To provide the first estimates of the risk of suicide after bereavementby the suicide of any first-degree relative and the proportion of suicides inDenmark attributable to suicide bereavement.Methods:We conducted a nationwide nested case–control study definingcases as all Danish-born individuals who died by suicide in Denmark between01 January 1980 and 31 December 2016 (n=32,248), age-matched to four liv-ing controls. Using three exposure categories (bereavement by the suicide of arelative [parent, offspring, sibling, and spouse/cohabitee]; non-suicide bereave-ment; no bereavement) and conditional logistic regression adjusted for pre-specified covariates we estimated the odds of exposure to suicide bereavementin cases versus controls. We tested whether associations differed for men andwomen, estimated the population attributable fraction (PAF) of suicides in ourpopulation at risk that could be attributed to a first-degree relative's suicideloss, and estimated the attributable fraction among the exposed (AFe).Results:Suicide bereavement was associated with an increased odds of suicidewhen compared with no bereavement (ORadj2=2.90, 95% CI: 2.46–3.40) ornon-suicide bereavement (ORadj2=1.48, 95% CI: 1.25–1.74). There was no evi-dence to support any interaction with sex. PAF (0.69%; 95% CI: 0.62%–0.77%)and AFe (60.12%; 95% CI: 53.19%–66.03%) estimates suggested that inDenmark 0.69% of suicides, and 60% of suicides among suicide-bereaved rela-tives, could be prevented if it was possible to address all factors increasing sui-cide risk in suicide-bereaved relatives.Conclusion:Suicide bereavement in relatives and partners contributes to atleast one in 145 suicides in Denmark.

Type: Article
Title: Proportion of suicides in Denmark attributable to bereavement by the suicide of a first-degree relative or partner: nested case-control study
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1111/acps.13493
Publisher version: https://doi.org/10.1111/acps.13493
Language: English
Additional information: © 2022 The Authors. Acta Psychiatrica Scandinavica published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Keywords: bereavement, case–control studies, population attributable fraction, registries, suicide
UCL classification: UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry > Epidemiology and Applied Clinical Research
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry
URI: https://discovery-pp.ucl.ac.uk/id/eprint/10154828
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