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Safety Considerations and Proposed Workflow for Laboratory-Scale Chemical Synthesis by Ball Milling

Priestley, I; Battilocchio, C; Iosub, AV; Barreteau, F; Bluck, GW; Ling, KB; Ingram, K; ... Browne, DL; + view all (2023) Safety Considerations and Proposed Workflow for Laboratory-Scale Chemical Synthesis by Ball Milling. Organic Process Research and Development , 27 (2) pp. 269-275. 10.1021/acs.oprd.2c00226. Green open access

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Abstract

Chemical reactions that take place in a ball mill and in the absence of a bulk reaction solvent present different safety profiles to stirred solution reactions. Herein, we present and describe steps that a researcher may take to better ensure that they have considered some of the hazards and measures that emerge and minimize the risk to themselves and their colleagues.

Type: Article
Title: Safety Considerations and Proposed Workflow for Laboratory-Scale Chemical Synthesis by Ball Milling
Open access status: An open access version is available from UCL Discovery
DOI: 10.1021/acs.oprd.2c00226
Publisher version: https://doi.org/10.1021/acs.oprd.2c00226
Language: English
Additional information: This work is licensed under an Attribution 4.0 International License (CC BY 4.0).
Keywords: Ball milling, mechanochemistry, safety, laboratory scale
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy > Pharma and Bio Chemistry
URI: https://discovery-pp.ucl.ac.uk/id/eprint/10165065
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