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Meshless Simulation of Multi-site Radio Frequency Catheter Ablation through the Fragile Points Method

Mountris, K; Schilling, R; Casals, A; Wurdemann, Helge; (2023) Meshless Simulation of Multi-site Radio Frequency Catheter Ablation through the Fragile Points Method. In: Proceedings of the International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE: Sydney, Australia. (In press). Green open access

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Abstract

Computational models for radio frequency catheter ablation (RFCA) of cardiac arrhythmia have been developed and tested in conditions where a single ablation site is considered. However, in reality arrhythmic events are generated at multiple sites which are ablated during treatment. Under such conditions, heat accumulation from several ablations is expected and models should take this effect into account. Moreover, such models are solved using the Finite Element Method which requires a good quality mesh to ensure numerical accuracy. Therefore, clinical application is limited since heat accumulation effects are neglected and numerical accuracy depends on mesh quality. In this work, we propose a novel meshless computational model where tissue heat accumulation from previously ablated sites is taken into account. In this way, we aim to overcome the mesh quality restriction of the Finite Element Method and enable realistic multi-site ablation simulation. We consider a two ablation sites protocol where tissue temperature at the end of the first ablation is used as initial condition for the second ablation. The effect of the time interval between the ablation of the two sites is evaluated. The proposed method demonstrates that previous models that do not account for heat accumulation between ablations may underestimate the tissue heat distribution.

Type: Proceedings paper
Title: Meshless Simulation of Multi-site Radio Frequency Catheter Ablation through the Fragile Points Method
Event: 45th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
Open access status: An open access version is available from UCL Discovery
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Mechanical Engineering
URI: https://discovery-pp.ucl.ac.uk/id/eprint/10169141
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