Stanziola, Antonio;
Pineda-Pardo, José A;
Treeby, Bradley;
(2023)
Transcranial ultrasound simulation with uncertainty estimation.
JASA Express Letters
, 3
(5)
, Article 052001. 10.1121/10.0019380.
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Abstract
Transcranial ultrasound simulations are increasingly used to predict in situ exposure parameters for ultrasound therapies in the brain. However, there can be considerable uncertainty in estimating the acoustic medium properties of the skull and brain from computed tomography (CT) images. This paper shows how the resulting uncertainty in the simulated acoustic field can be predicted in a computationally efficient way using linear uncertainty propagation. Results for a representative transcranial simulation using a focused bowl transducer at 500 kHz show good agreement with unbiased uncertainty estimates obtained using Monte Carlo.
| Type: | Article |
|---|---|
| Title: | Transcranial ultrasound simulation with uncertainty estimation |
| Location: | United States |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1121/10.0019380 |
| Publisher version: | https://doi.org/10.1121/10.0019380 |
| Language: | English |
| Additional information: | © 2023 Author(s). All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
| Keywords: | Uncertainty, Ultrasonography, Computer Simulation, Brain, Skull |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10170148 |
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