Testi, Ilaria;
Brandão-de-Resende, Camilo;
De-La-Torre, Alejandra;
Concha-Del-Rio, Luz Elena;
Cheja-Kalb, Rashel;
Mahendradas, Padmamalini;
Habot-Wilner, Zohar;
... Solebo, Ameenat Lola; + view all
(2023)
Ocular Inflammatory Events Following COVID-19 Vaccination in the Paediatric Population: A Multinational Case Series.
Ocular Immunology and Inflammation
10.1080/09273948.2023.2220782.
(In press).
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Abstract
BACKGROUND: Ocular inflammatory events following COVID-19 vaccination have been reported in the adult population. METHODS: Multinational case series of patients under the age of 18 diagnosed with ocular inflammatory events within 28 days of COVID-19 vaccination. RESULTS: Twenty individuals were included. The most common event was anterior uveitis (n = 8, 40.0%), followed by intermediate uveitis (7 patients, 35%), panuveitis (4 patients, 20%), and posterior uveitis (1 patient, 5%). The event was noticed in the first week after vaccination in 11 patients (55.0%). Twelve patients (60.0%) had a previous history of intraocular inflammatory event. Patients were managed with topical corticosteroids (n = 19, 95.0%), oral corticosteroids (n = 10, 50.0%), or increased dose of immunosuppressive treatment (n = 6, 30.0%). Thirteen patients (65.0%) had a complete resolution of the ocular event without complications. All patients had a final visual acuity unaffected or less than three lines of loss. CONCLUSION: Ocular inflammatory events may happen in the paediatric population following COVID-19 vaccination. Most events were successfully treated, and all showed a good visual outcome.
Type: | Article |
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Title: | Ocular Inflammatory Events Following COVID-19 Vaccination in the Paediatric Population: A Multinational Case Series |
Open access status: | An open access version is available from UCL Discovery |
DOI: | 10.1080/09273948.2023.2220782 |
Publisher version: | https://doi.org/10.1080/09273948.2023.2220782 |
Language: | English |
Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
Keywords: | Paediatric; Uveitis; Ocular inflammation; Coronavirus; COVID-19; SARS-CoV2; Vaccination |
UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Population, Policy and Practice Dept |
URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10172129 |
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