Yao, Junke;
Bosi, Giorgia Maria;
Burriesci, Gaetano;
Wurdemann, Helge;
(2023)
Compliant Aortic Annulus Sizing with Different Elliptical Ratios Through a Valvuloplasty Balloon Catheter.
IEEE Transactions on Biomedical Engineering
10.1109/TBME.2023.3289300.
(In press).
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Abstract
Objective : Aortic stenos (AS) is a heart valve disease that commonly affects the elderly. Transcatheter aortic valve implantation is a minimally invasive treatment that allows to replace the function of the diseased native valve with a prosthetic device, relying on catheters for device implantation. According to the current clinical guidelines, the choice of the implanted device is based on preoperative sizing determined by image-based technology. However, this assessment faces inherent limitations that can lead to sub-optimal sizing of the prosthesis; in turn, this can cause major post-operative complications like aortic regurgitation or cardiac electrical signal disruption. Method : By utilizing balloon pressure and volume data, this paper proposes an intra-operative method for determining the dimension of the aortic annulus which takes into account its compliance and geometric irregularity. The intra-balloon pressure-volume curves were obtained using an Automated Balloon Inflation Device operating a commercially available valvuloplasty balloon catheter. A sizing algorithm to estimate the dimensions of the annulus was integrated via a validated analytical model and a numerical model for balloon free-inflation. Tests were performed on circular and elliptical idealised aortic phantoms. Results : Experimental results confirm that the pressure-volume data processed with the sizing algorithm can be used to determine the circular annular diameter for all tissue rigidities. Conclusion : The measurement of stiffer elliptical annulus phantoms shows good accuracy and high repeatability. Significance : This work represents substantial progress toward improving the selection of TAVI devices by using balloon catheters to improve the sizing of compliant aortic annuli with complex geometry.
| Type: | Article |
|---|---|
| Title: | Compliant Aortic Annulus Sizing with Different Elliptical Ratios Through a Valvuloplasty Balloon Catheter |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1109/TBME.2023.3289300 |
| Publisher version: | https://doi.org/10.1109/TBME.2023.3289300 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | Balloon Valvuloplasty Catheters, Balloon Sizing,TAVI, Aortic Stenosis, Aortic Annulus, Balloon Aortic Valvuloplasty |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Mechanical Engineering |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10172405 |
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