Sud, A;
Horton, RH;
Hingorani, AD;
Tzoulaki, I;
Turnbull, C;
Houlston, RS;
Lucassen, A;
(2023)
Realistic expectations are key to realising the benefits of polygenic scores.
BMJ
, 380
, Article e073149. 10.1136/bmj-2022-073149.
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Abstract
We must not let enthusiasm around polygenic scores allow us to forget other factors that are bigger, more modifiable, and relevant for everyone, argue Amit Sud, Rachel Horton, and colleagues
Type: | Article |
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Title: | Realistic expectations are key to realising the benefits of polygenic scores |
Location: | England |
Open access status: | An open access version is available from UCL Discovery |
DOI: | 10.1136/bmj-2022-073149 |
Publisher version: | https://doi.org/10.1136/bmj-2022-073149 |
Language: | English |
Additional information: | This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/. |
Keywords: | Humans, Multifactorial Inheritance, Disease, Risk |
UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science |
URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10172553 |
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