Itzkowitz, N;
Gong, X;
Atilola, G;
Konstantinoudis, G;
Adams, K;
Jephcote, C;
Gulliver, J;
... Blangiardo, M; + view all
(2023)
Aircraft noise and cardiovascular morbidity and mortality near Heathrow Airport: A case-crossover study.
Environment International
, 177
, Article 108016. 10.1016/j.envint.2023.108016.
(In press).
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Abstract
Aircraft noise causes annoyance and sleep disturbance and there is some evidence of associations between long-term exposures and cardiovascular disease (CVD). We investigated short-term associations between previous day aircraft noise and cardiovascular events in a population of 6.3 million residing near Heathrow Airport using a case-crossover design and exposure data for different times of day and night. We included all recorded hospitalisations (n = 442,442) and deaths (n = 49,443) in 2014–2018 due to CVD. Conditional logistic regression was used to estimate the ORs and adjusted for NO2 concentration, temperature, and holidays. We estimated an increase in risk for 10 dB increment in noise during the previous evening (Leve OR = 1.007, 95% CI 0.999–1.015), particularly from 22:00–23:00 h (OR = 1.007, 95% CI 1.000–1.013), and the early morning hours 04:30–06:00 h (OR = 1.012, 95% CI 1.002–1.021) for all CVD admissions, but no significant associations with day-time noise. There was effect modification by age-sex, ethnicity, deprivation, and season, and some suggestion that high noise variability at night was associated with higher risks. Our findings are consistent with proposed mechanisms for short-term impacts of aircraft noise at night on CVD from experimental studies, including sleep disturbance, increases in blood pressure and stress hormone levels and impaired endothelial function.
| Type: | Article |
|---|---|
| Title: | Aircraft noise and cardiovascular morbidity and mortality near Heathrow Airport: A case-crossover study |
| Location: | Netherlands |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.envint.2023.108016 |
| Publisher version: | https://doi.org/10.1016/j.envint.2023.108016 |
| Language: | English |
| Additional information: | © 2023 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
| Keywords: | Aircraft noise, Cardiovascular disease, Case-crossover, Epidemiology, Hospitalisation, Mortality, Short-term association, Humans, Cross-Over Studies, Noise, Transportation, Airports, Cardiovascular Diseases, Aircraft, Environmental Exposure |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Population, Policy and Practice Dept |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10172759 |
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