Perez-Lara, Maria L;
Khong, Jia C;
Wilson, Matthew D;
Cline, Ben D;
Moss, Robert M;
(2023)
First Study of a HEXITEC Detector for Secondary Particle Characterisation during Proton Beam Therapy.
Applied Sciences
, 13
(13)
, Article 7735. 10.3390/app13137735.
Preview |
PDF
Moss_First Study of a HEXITEC Detector for Secondary Particle Characterisation during Proton Beam Therapy_VoR.pdf - Published Version Download (394kB) | Preview |
Abstract
Online proton range verification is a rapidly emerging field characterised by its ability to reduce the error margins during proton beam therapy, as it is patient-specific and in vivo. In particular, secondary prompt gamma detection is a promising tool to monitor the dose delivery. The present research evaluates the capability of a HEXITEC detector to identify the prompt gammas produced during proton beam therapy, and assesses its potential for online range verification. To achieve this, the detector is placed at one side of a water phantom, which is irradiated at different proton energies in the University College London Hospital Proton Centre. For further analysis, Monte Carlo simulations are performed using Geant4 and the same geometry as the experiment. The results show that HEXITEC has the potential to be part of a detection system that could identify secondary prompt gammas within the secondary field produced inside the target, allowing for the in-detector discrimination of these particles via cluster size analysis. The comparison between data sets shows that there is a high level of accuracy between the model and the experimental measurements in terms of secondary flux and charge diffusion inside the detector, which poses the model as a fundamental tool for future optimisation studies.
| Type: | Article |
|---|---|
| Title: | First Study of a HEXITEC Detector for Secondary Particle Characterisation during Proton Beam Therapy |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.3390/app13137735 |
| Publisher version: | https://doi.org/10.3390/app13137735 |
| Language: | English |
| Additional information: | This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third-party material in this article are included in the Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
| Keywords: | HEXITEC detector; Geant4; proton beam therapy; prompt gamma detection; proton range monitoring |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10173599 |
Archive Staff Only
 |
View Item |
