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Coffee Consumption and Risk of Hypertension in Adults: Systematic Review and Meta-Analysis

Haghighatdoost, Fahimeh; Hajihashemi, Parisa; de Sousa Romeiro, Amanda Maria; Mohammadifard, Noushin; Sarrafzadegan, Nizal; de Oliveira, Cesar; Silveira, Erika Aparecida; (2023) Coffee Consumption and Risk of Hypertension in Adults: Systematic Review and Meta-Analysis. Nutrients , 15 (13) , Article 3060. 10.3390/nu15133060. Green open access

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Abstract

OBJECTIVES: The association between coffee intake and hypertension (HTN) risk is controversial. Therefore, this systematic review and meta-analysis aimed at summarizing the current evidence on the association of coffee with hypertension risk in observational studies. METHODS: PubMed/Medline and Web of Science were searched for observational studies up to February 2023. Observational studies which assessed the risk of HTN in the highest category of coffee consumption in comparison with the lowest intake were included in the current meta-analysis (registration number: CRD42022371494). The pooled effect of coffee on HTN was evaluated using a random-effects model. RESULTS: Twenty-five studies i.e., thirteen cross-sectional studies and twelve cohorts were identified to be eligible. Combining 13 extracted effect sizes from cohort studies showed that higher coffee consumption was associated with 7% reduction in the risk of HTN (95% CI: 0.88, 0.97; I2: 22.3%), whereas combining 16 effect sizes from cross-sectional studies illustrated a greater reduction in HTN risk (RR = 0.79, 95% CI: 0.72, 0.87; I2 = 63.2%). These results varied by studies characteristics, such as the region of study, participants' sex, study quality, and sample size. CONCLUSIONS: An inverse association was found between coffee consumption and hypertension risk in both cross-sectional and cohort studies. However, this association was dependent on studies characteristics. Further studies considering such factors are required to confirm the results of this study.

Type: Article
Title: Coffee Consumption and Risk of Hypertension in Adults: Systematic Review and Meta-Analysis
Location: Switzerland
Open access status: An open access version is available from UCL Discovery
DOI: 10.3390/nu15133060
Publisher version: https://doi.org/10.3390/nu15133060
Language: English
Additional information: © 2023 by the Authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Keywords: blood pressure, coffee, hypertension, meta-analysis
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Epidemiology and Public Health
URI: https://discovery-pp.ucl.ac.uk/id/eprint/10173606
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