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Recent developments in the use of centrifugal spinning and pressurized gyration for biomedical applications

Ahmed, J; Gultekinoglu, M; Edirisinghe, M; (2023) Recent developments in the use of centrifugal spinning and pressurized gyration for biomedical applications. Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology , Article e1916. 10.1002/wnan.1916. (In press). Green open access

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Abstract

Centrifugal spinning is a technology used to generate small diameter fibers and has been extensively studied for its vast applications in biomedical engineering. Centrifugal spinning is known for its rapid production rate and has inspired the creation of other technologies which leverage the high-speed rotation, namely Pressurized Gyration. Pressurized gyration incorporates a unique applied gas pressure which serves to provide additional control over the fiber production process. The resulting fibers are uniquely suitable for a range of healthcare-related applications that are thoroughly discussed in this work, which involve scaffolds for tissue engineering, solid dispersions for drug delivery, antimicrobial meshes for filtration and bandage-like fibrous coverings for wound healing. In this review, the notable recent developments in centrifugal spinning and pressurized gyration are presented and how these technologies are being used to further the range of uses of biomaterials engineering, for example the development of core-sheath fabrication techniques for multi-layered fibers and the combination with electrospinning to produce advanced fiber mats. The enormous potential of these technologies and their future advancements highlights how important they are in the biomedical discipline.

Type: Article
Title: Recent developments in the use of centrifugal spinning and pressurized gyration for biomedical applications
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1002/wnan.1916
Publisher version: https://doi.org/10.1002/wnan.1916
Language: English
Additional information: © 2023 The Authors. WIREs Nanomedicine and Nanobiotechnology published by Wiley Periodicals LLC. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Keywords: biomedical applications, centrifugal spinning, fibres, polymers, pressurised gyration
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Mechanical Engineering
URI: https://discovery-pp.ucl.ac.uk/id/eprint/10175382
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