UCL Discovery Stage
UCL home » Library Services » Electronic resources » UCL Discovery Stage

Hen egg white bovine colostrum supplement reduces symptoms of mild/moderate COVID-19: a randomized control trial

Mann, JK; Reddy, T; Der Stok, MV; Ngubane, A; Mulaudzi, T; Mchunu, N; Nevhungoni, P; ... Gosnell, BI; + view all (2023) Hen egg white bovine colostrum supplement reduces symptoms of mild/moderate COVID-19: a randomized control trial. Future Science OA , 9 (8) , Article FSO882. 10.2144/fsoa-2023-0024. Green open access

[thumbnail of fsoa-2023-0024.pdf]
Preview
Text
fsoa-2023-0024.pdf - Published Version

Download (1MB) | Preview

Abstract

Aim: The ability of a hen egg white bovine colostrum supplement to prevent severe COVID-19 was tested in a double-blind randomized control study. Methods: Adults with mild/moderate COVID-19, risk factors for severe disease, and within 5 days of symptom onset were assigned to the intervention (n = 77) or placebo (n = 79) arms. Symptoms were documented until day 42 post-enrollment and viral clearance was assessed at 11-13 days post-symptom onset. Results: One participant developed severe COVID-19. The severe-type symptom score was lower in the active arm at 11-13 days post-symptom onset (p = 0.049). Chest pain, fever/chills, joint pain/malaise, and sore throat were significantly less frequent in the active arm. No differences in viral clearance were observed. Conclusion: The intervention reduced symptoms of mild/moderate COVID-19.

Type: Article
Title: Hen egg white bovine colostrum supplement reduces symptoms of mild/moderate COVID-19: a randomized control trial
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.2144/fsoa-2023-0024
Publisher version: https://doi.org/10.2144/fsoa-2023-0024
Language: English
Additional information: This work is licensed under the Creative Commons Attribution 4.0 License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
Keywords: COVID-19, colostrum, coronavirus, delta, egg white, lactoferrin, lysozyme, nutritional supplement, omicron, ovotransferrin
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Infection and Immunity
URI: https://discovery-pp.ucl.ac.uk/id/eprint/10177020
Downloads since deposit
612Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item