Toribio-Vázquez, C;
Gómez Rivas, J;
Amigo, F;
Carrión, DM;
Yebes, Á;
Alonso-Bartolomé, M;
Ayllon, H;
... IDENTIFY Study group; + view all
(2024)
Prevalence of urinary tract cancer in the Spanish cohort of the IDENTIFY study
//
Prevalencia del cáncer del tracto urinario. Análisis de la cohorte española del estudio IDENTIFY.
Actas Urológicas Españolas (English Edition)
, 48
(3)
pp. 228-237.
10.1016/j.acuroe.2023.08.001.
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Abstract
Introduction: Malignant tumors of the urinary tract are associated with high morbidity and mortality, and their prevalence can vary worldwide. Recently, the IDENTIFY study has published results on the prevalence of urinary tract cancer at a global level. This study evaluates the prevalence of cancer within the Spanish cohort of the IDENTIFY study to determine whether the published results can be extrapolated to our population. // Patients and methods: An analysis of the data from the Spanish cohort of patients in the IDENTIFY study was performed. This is a prospective cohort of patients referred to secondary care with suspected cancer, predominantly due to hematuria. Patients were recruited between December 2017 and December 2018. // Results: A total of 706 patients from 9 Spanish centers were analyzed. Of these, 277 (39.2%) were diagnosed with cancer: 259 (36.7%) bladder cancer, 10 (1.4%) upper tract urothelial carcinoma, 9 (1.2%) renal cancer and 5 (0.7%) prostate cancer. Increasing age (OR 1.05 (95% CI 1.03−1.06; P < 0.001)), visible hematuria (VH) OR 2.19 (95% CI 1.13–4.24; P = 0.02)) and smoking (ex-smokers: OR 2.11(95% CI 1.30–3.40; P = 0.002); smokers: OR 2.36 (95% CI 1.40–3.95; P = 0.001)) were associated with higher probability of bladder cancer. // Conclusion: This study highlights the risk of bladder cancer in patients with VH and smoking habits. Bladder cancer presented the highest prevalence; higher than the prevalence reported in previous series and presented in the IDENTIFY study. Future work should evaluate other associated factors that allow us to create cancer prediction models to improve the detection of cancer in our patients.
| Type: | Article |
|---|---|
| Title: | Prevalence of urinary tract cancer in the Spanish cohort of the IDENTIFY study // Prevalencia del cáncer del tracto urinario. Análisis de la cohorte española del estudio IDENTIFY |
| Location: | Spain |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.acuroe.2023.08.001 |
| Publisher version: | https://doi.org/10.1016/j.acuroe.2023.08.001 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10177724 |
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