Zamberlan, Francesco;
Castagnolo, Daniele;
Sarkar, Paramita;
Schultz, Dani;
(2023)
Looking back and moving forward in medicinal chemistry.
Nature Communications
, 14
, Article 4299. 10.1038/s41467-023-39949-6.
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Abstract
Medicinal chemistry is a fast-evolving interdisciplinary research area which aims to improve human life by developing drugs to combat diseases. Nature Communications interviewed three scientists, Daniele Castagnolo (Associate Professor at University College London), Paramita Sarkar (postdoctoral researcher at University of Würzburg) and Dani Schulz (Director, Discovery Process Chemistry at Merck), about their careers and the past and future in medicinal chemistry research. We asked the researchers what medicinal chemistry means to them, and their opinions on the current relevance of the Rule of Five and new chemical modalities beyond the Rule of Five. We also discuss the differences between academic and industry research in medicinal chemistry and how Open Science can support collaborations for drug development.
| Type: | Article |
|---|---|
| Title: | Looking back and moving forward in medicinal chemistry |
| Location: | England |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1038/s41467-023-39949-6 |
| Publisher version: | https://doi.org/10.1038/s41467-023-39949-6 |
| Language: | English |
| Additional information: | This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
| Keywords: | Science & Technology, Multidisciplinary Sciences, Science & Technology - Other Topics |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > Dept of Chemistry |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10179138 |
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