Zhao, Tianrui;
Pham, Truc T;
Baker, Christian;
Ma, Michelle T;
Ourselin, Sebastien;
Vercauteren, Tom;
Zhang, Edward;
... Xia, Wenfeng; + view all
(2023)
All-optical multimode fibre photoacoustic endomicroscopy with scalable spatial resolution and field-of-view.
In: Kim, Chulhong and Laufer, Jan and Ntziachristos, Vasilis and Zemp, Roger J, (eds.)
Proceedings Volume 12631, Opto-Acoustic Methods and Applications in Biophotonics VI.
(pp. 126310M).
SPE: Munich, Germany.
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Abstract
An all-optical, forward-viewing, optical-resolution photoacoustic endomicroscopy probe was developed for guiding minimally invasive procedures. The probe comprises a multimode fibre for the delivery of excitation laser via wavefront shaping, and a fibre-optic ultrasound sensor based on a plane-concave microresonator at the tip of a single-mode fibre. High-resolution photoacoustic microscopy images of mouse red blood cells and mouse ear vasculature were acquired, and the high scalability of the probe in terms of field-of-view and spatial resolution was demonstrated. The ultrathin photoacoustic endomicroscopy probe promises to guide minimally invasive surgery by providing both molecular and microstructural information.
| Type: | Proceedings paper |
|---|---|
| Title: | All-optical multimode fibre photoacoustic endomicroscopy with scalable spatial resolution and field-of-view |
| Event: | European Conferences on Biomedical Optics 2023 |
| ISBN-13: | 9781510664715 |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1117/12.2670411 |
| Publisher version: | https://doi.org/10.1117/12.2670411 |
| Language: | English |
| Additional information: | This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10179357 |
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