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Evaluation of hyperspectral imaging measurements of changes in hemoglobin oxygenation and oxidation of cytochrome-c-oxidase using a liquid blood phantom

Caredda, Charly; Lange, Frédéric; Tachtsidis, Ilias; Montcel, Bruno; (2023) Evaluation of hyperspectral imaging measurements of changes in hemoglobin oxygenation and oxidation of cytochrome-c-oxidase using a liquid blood phantom. In: Contini, Davide and Hoshi, Yoko and O'Sullivan, Thomas D, (eds.) Proceedings of SPIE Volume 12628 - The International Society for Optical Engineering. (pp. 126280Q). SPIE: Munich, Germany. Green open access

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Abstract

Optical imaging is a non-invasive technique that is able to monitor hemodynamic and metabolic responses during neurosurgery. However, a robust quantification is complicated to perform. To overcome this issue, phantoms that mimic biological tissues are required for the development of imaging systems in order to reach a true standardization. In this work, we explore the possibility to use a combined liquid blood phantom with cytochrome contained yeast to evaluate the reliability of hyperspectral imaging to measure oxygenation and metabolic changes. This phantom can be used to verify the reliability of intraoperative optical setups before moving on to clinical application.

Type: Proceedings paper
Title: Evaluation of hyperspectral imaging measurements of changes in hemoglobin oxygenation and oxidation of cytochrome-c-oxidase using a liquid blood phantom
Event: European Conferences on Biomedical Optics 2023
ISBN-13: 9781510664654
Open access status: An open access version is available from UCL Discovery
DOI: 10.1117/12.2670746
Publisher version: https://doi.org/10.1117/12.2670746
Language: English
Additional information: This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery-pp.ucl.ac.uk/id/eprint/10179359
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