Ridgway, Wesley;
Dalwadi, Mohit;
Pearce, Philip;
Chapman, S Jon;
(2023)
Motility-Induced Phase Separation Mediated by Bacterial Quorum Sensing.
Physical Review Letters
, 131
, Article 228302. 10.1103/PhysRevLett.131.228302.
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Abstract
We study motility-induced phase separation (MIPS) in living active matter, in which cells interact through chemical signaling, or quorum sensing. In contrast to previous theories of MIPS, our multiscale continuum model accounts explicitly for genetic regulation of signal production and motility. Through analysis and simulations, we derive a new criterion for the onset of MIPS that depends on features of the genetic network. Furthermore, we identify and characterize a new type of oscillatory instability that occurs when gene regulation inside cells promotes motility in higher signal concentrations.
| Type: | Article |
|---|---|
| Title: | Motility-Induced Phase Separation Mediated by Bacterial Quorum Sensing |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1103/PhysRevLett.131.228302 |
| Publisher version: | https://doi.org/10.1103/PhysRevLett.131.228302 |
| Language: | English |
| Additional information: | Published by the American Physical Society under the terms of the Creative Commons Attribution 4.0 International license. Further distribution of this work must maintain attribution to the author(s) and the published article’s title, journal citation, and DOI. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > Dept of Mathematics |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10180129 |
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