Mercante, Luiza A;
Teodoro, Kelcilene BR;
dos Santos, Danilo M;
dos Santos, Francisco V;
Ballesteros, Camilo AS;
Ju, Tian;
Williams, Gareth R;
(2023)
Recent Progress in Stimuli-Responsive Antimicrobial Electrospun Nanofibers.
Polymers
, 15
(21)
, Article 4299. 10.3390/polym15214299.
Preview |
Text
polymers-15-04299-v2.pdf - Published Version Download (9MB) | Preview |
Abstract
Electrospun nanofibrous membranes have garnered significant attention in antimicrobial applications, owing to their intricate three-dimensional network that confers an interconnected porous structure, high specific surface area, and tunable physicochemical properties, as well as their notable capacity for loading and sustained release of antimicrobial agents. Tailoring polymer or hybrid-based nanofibrous membranes with stimuli-responsive characteristics further enhances their versatility, enabling them to exhibit broad-spectrum or specific activity against diverse microorganisms. In this review, we elucidate the pivotal advancements achieved in the realm of stimuli-responsive antimicrobial electrospun nanofibers operating by light, temperature, pH, humidity, and electric field, among others. We provide a concise introduction to the strategies employed to design smart electrospun nanofibers with antimicrobial properties. The core section of our review spotlights recent progress in electrospun nanofiber-based systems triggered by single- and multi-stimuli. Within each stimulus category, we explore recent examples of nanofibers based on different polymers and antimicrobial agents. Finally, we delve into the constraints and future directions of stimuli-responsive nanofibrous materials, paving the way for their wider application spectrum and catalyzing progress toward industrial utilization.
| Type: | Article |
|---|---|
| Title: | Recent Progress in Stimuli-Responsive Antimicrobial Electrospun Nanofibers |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.3390/polym15214299 |
| Publisher version: | https://doi.org/10.3390/polym15214299 |
| Language: | English |
| Additional information: | © 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
| Keywords: | electrospinning; electrospun nanofibers; stimuli-responsive; smart materials; light-responsive; pH-responsive; thermo-responsive; antimicrobial; antibacterial |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy > Pharmaceutics |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10180718 |
Archive Staff Only
 |
View Item |
