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Inkjet Printing of Pharmaceuticals

Carou‐Senra, Paola; Rodríguez‐Pombo, Lucía; Awad, Atheer; Basit, Abdul W; Alvarez‐Lorenzo, Carmen; Goyanes, Alvaro; (2023) Inkjet Printing of Pharmaceuticals. Advanced Materials , Article 2309164. 10.1002/adma.202309164. (In press). Green open access

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Abstract

Inkjet printing (IJP) is an additive manufacturing process that selectively deposits ink materials, layer-by-layer, to create 3D objects or 2D patterns with precise control over their structure and composition. This technology has emerged as an attractive and versatile approach to address the ever-evolving demands of personalized medicine in the healthcare industry. Although originally developed for nonhealthcare applications, IJP harnesses the potential of pharma-inks, which are meticulously formulated inks containing drugs and pharmaceutical excipients. Delving into the formulation and components of pharma-inks, the key to precise and adaptable material deposition enabled by IJP is unraveled. The review extends its focus to substrate materials, including paper, films, foams, lenses, and 3D-printed materials, showcasing their diverse advantages, while exploring a wide spectrum of therapeutic applications. Additionally, the potential benefits of hardware and software improvements, along with artificial intelligence integration, are discussed to enhance IJP's precision and efficiency. Embracing these advancements, IJP holds immense potential to reshape traditional medicine manufacturing processes, ushering in an era of medical precision. However, further exploration and optimization are needed to fully utilize IJP's healthcare capabilities. As researchers push the boundaries of IJP, the vision of patient-specific treatment is on the horizon of becoming a tangible reality.

Type: Article
Title: Inkjet Printing of Pharmaceuticals
Open access status: An open access version is available from UCL Discovery
DOI: 10.1002/adma.202309164
Publisher version: https://doi.org/10.1002/adma.202309164
Language: English
Additional information: Copyright © 2023 The Authors. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
Keywords: bioprinting, digital healthcare and industry 4.0, drop-on-demand and continuous ink-jet additive manufacturing, personalized medications, precision medicine, printing pharmaceuticals using pharma-inks, quick response (QR) codes and data matrix patterns
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy > Pharmaceutics
URI: https://discovery-pp.ucl.ac.uk/id/eprint/10181477
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