Doersam, Annica Franziska;
Moser, Julia;
Throm, Jana;
Weiss, Magdalene;
Zipfel, Stephan;
Micali, Nadia;
Preissl, Hubert;
(2022)
Maternal eating disorder severity is associated with increased latency of foetal auditory event-related brain responses.
European Eating Disorders Review
, 30
(1)
pp. 75-81.
10.1002/erv.2870.
Preview |
PDF
Maternal eating disorder severity.pdf - Published Version Download (476kB) | Preview |
Abstract
Objective: Maternal eating disorders (EDs) are associated with adverse pregnancy and child outcomes. There is limited research investigating the influence of maternal EDs on foetal brain development. Method: Using foetal magnetoencephalography (fMEG), an auditory sequence was presented for 10 min to assess brain response latencies in foetuses of mothers with (n = 12) and without (n = 11) a history of anorexia nervosa (AN) in the third trimester of pregnancy. ED history and severity were assessed using the structured clinical expert interview eating disorder examination (EDE) and the self-report questionnaire EDE-Q. Results: Foetuses of mothers with AN showed delayed foetal brain responses to auditory stimulation compared to foetuses of control women. Self-reported ED symptom severity explained 34% of variance in foetal brain response latencies in the AN group. Conclusions: ED pathology was strongly associated with foetal brain response latencies in the third trimester with longer latencies in foetuses of women with a history of AN reporting more ED symptoms. Follow-up on the children is pivotal to investigate if fMEG outcomes are associated with later child development.
| Type: | Article |
|---|---|
| Title: | Maternal eating disorder severity is associated with increased latency of foetal auditory event-related brain responses |
| Location: | England |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1002/erv.2870 |
| Publisher version: | https://doi.org/10.1002/erv.2870 |
| Language: | English |
| Additional information: | © 2021 The Authors. European Eating Disorders Review published by Eating Disorders Association and John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
| Keywords: | Social Sciences, Psychology, Clinical, Psychology, anorexia nervosa, brain, development, eating disorders, foetus, fMEG, pregnancy, EVOKED FIELDS, MAGNETOENCEPHALOGRAPHY, CHILDHOOD, ANOREXIA, CHILDREN, NERVOSA, MOTHERS, WOMEN |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Population, Policy and Practice Dept |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10181850 |
Archive Staff Only
 |
View Item |
