Nugawela, Manjula D;
Pinto Pereira, Snehal M;
Rojas, Natalia K;
McOwat, Kelsey;
Simmons, Ruth;
Dalrymple, Emma;
Ford, Tamsin;
... CLoCk Consortium; + view all
(2023)
Data Resource Profile: the Children and Young People with Long COVID (CLoCk) Study.
International Journal of Epidemiology
, Article dyad158. 10.1093/ije/dyad158.
(In press).
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Abstract
Key Features: The Children and Young People with Long COVID (CLoCk) study is a national matched prospective study which was set up with the aims of (i) describing the clinical phenotype of post-COVID symptomology in children and young people (CYP), (ii) producing a research definition for long COVID in CYP and (iii) establishing the prevalence of long COVID in CYP. In total, 219 175 CYP aged 11–17 years, who were tested for SARS-CoV-2 via polymerase chain reaction (PCR) testing between September 2020 and March 2021 in England, were invited to participate. Test-positive and test-negative CYP were matched at study invitation on month of test, age, sex and geographical region. CYP were enrolled into the study at 3, 6 or 12 months after their index PCR test (n = 31 012). Depending on when they enrolled, they were also invited to fill in follow-up questionnaires at 6, 12 and 24 months after their index test. The overall response rate was 14.1%, with retention across sweeps varying from 36.6% to 54.1%. The dataset includes information on physical and mental health using validated scales over time, allowing for examination of within-individual change. CYP report symptoms themselves rather than relying on parental report or administrative records. Requests for access to the participant-level data from this study can be submitted via email to: [Clock@ukhsa.gov.uk].
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