Curtis, David;
(2023)
Social scientists would do well to steer clear of polygenic scores.
Behavioral and Brain Sciences
, 46
, Article e212. 10.1017/S0140525X22002448.
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Abstract
The problems with polygenic scores (PGSs) have been understated. The fact that they are ancestry-specific means that biases related to sociodemographic factors would be impossible to avoid. Additionally, the requirement to obtain DNA would have profound impacts on study design and required resources, as well as likely introducing recruitment bias. PGSs are unhelpful for social science research.
Type: | Article |
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Title: | Social scientists would do well to steer clear of polygenic scores |
Location: | England |
Open access status: | An open access version is available from UCL Discovery |
DOI: | 10.1017/S0140525X22002448 |
Publisher version: | http://dx.doi.org/10.1017/s0140525x22002448 |
Language: | English |
Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Genetics, Evolution and Environment |
URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10184546 |
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