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Changes in cardiovascular risk factors for diabetes among young versus older English adult populations

Basit, KA; Ng Fat, L; Gregg, EW; (2023) Changes in cardiovascular risk factors for diabetes among young versus older English adult populations. Journal of Public Health 10.1007/s10389-023-02143-5. (In press). Green open access

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Abstract

Background: To examine the prevalence of cardiovascular disease (CVD) risk factors among young, middle-aged and older adults with and without diabetes. Method: Among 23,501 participants of pooled nationally representative Health Survey for England years 2003, 2006, 2011 and 2017 (new sample was interviewed each year), CVD risk-factors associated with diabetes versus non-diabetes among young (18-54y), middle (55-74y) and older (≥ 75y) adults were assessed. Models were adjusted for age, sex, locality, ethnicity, qualification, survey year, cardiovascular disease, raised blood pressure, dyslipidaemia, combined obesity, current smoking, and excessive drinking. Results: 11.9% of adults had diabetes: prevalence was 5.3% in aged 18-54y, 18.1% in aged 55-74y, and 29.1% in older adults. Diabetes prevalence was higher in 2017 than 2003 in each age-group. After adjustments for confounding variables, significant predictors of diabetes among young were CVD history, raised BP, dyslipidaemia, combined obesity, and survey year 2006. Effect of dyslipidaemia in young adults on the risk of diabetes was stronger in more recent years 2006 (Odds Ratio =3.87), 2011 (3.04) and 2017 (3.42) as compared with 2003. Among middle age, CVD history, raised BP, dyslipidaemia, combined obesity and survey years 2006 and 2011 were significant predictors of diabetes whereas in older populations only dyslipidaemia, combined obesity and survey year 2011 showed strong association with risk of diabetes. Irrespective of age, smoking and excessive drinking were not significantly associated with diabetes. Conclusion: Young adults with diabetes have higher odds of having cardiovascular risk factors, with dyslipidaemia being the strongest risk factor. Early and specific intervention among young adults would delay CVD outcomes.

Type: Article
Title: Changes in cardiovascular risk factors for diabetes among young versus older English adult populations
Open access status: An open access version is available from UCL Discovery
DOI: 10.1007/s10389-023-02143-5
Publisher version: http://dx.doi.org/10.1007/s10389-023-02143-5
Language: English
Additional information: Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
Keywords: Cardiovascular risk factors · Diabetes · Age · Health examination survey · England
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Epidemiology and Public Health
URI: https://discovery-pp.ucl.ac.uk/id/eprint/10185204
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