Li, L;
Li, K;
Zhou, X;
Knowles, RL;
(2024)
Maximising the potential of Chinese birth cohort studies: a systematic review of mother–baby cohorts in mainland China.
Public Health
, 227
pp. 119-130.
10.1016/j.puhe.2023.11.035.
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Abstract
Objectives: There is now a growing interest in early-life influences on adult diseases in China. A number of birth cohorts have been established. This systematic review provided a better understanding of the development of mother–baby cohorts in China. // Study design: Systematic review. // Methods: We conducted a systematic review for research or profile papers in English/Chinese that reported data from mother–baby cohorts in mainland China, with ≥1y follow-up after birth. We identified 315 papers, corresponding to 31 cohorts from 19 provinces/megacities. // Results: All cohorts started in 1999–2017 (21 after 2010) and were set up with broad objectives or specific scientific focus. The baseline sample size varied, from <500 to >300,000 mothers. A majority of cohorts were initiated during pregnancy and followed children to <10y, only six to adolescence and none into adulthood. These cohorts mostly collected samples from mothers and babies, in addition to using interviews/questionnaires to collect information about pregnancy, birth and child health. Most cohorts were recruited from a single province/city. The large western region was understudied. // Conclusions: Mother–baby cohorts have developed rapidly in China, but usually with a short follow-up duration. Extending the follow-up of children and developing cross-cohort collaboration will increase the diversity, size and coverage of the sample, allow studying early influences on life-course health and identify targets for early intervention in the Chinese population.
| Type: | Article |
|---|---|
| Title: | Maximising the potential of Chinese birth cohort studies: a systematic review of mother–baby cohorts in mainland China |
| Location: | Netherlands |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.puhe.2023.11.035 |
| Publisher version: | http://dx.doi.org/10.1016/j.puhe.2023.11.035 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | Mother–baby cohort; Birth cohort; Environmental exposure; Maternal and child health; Life-course study; China; Systematic review |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10185931 |
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