Wierenga, LM;
Ruigrok, A;
Aksnes, ER;
Barth, C;
Beck, D;
Burke, S;
Crestol, A;
... Bos, MGN; + view all
(2024)
Recommendations for a Better Understanding of Sex and Gender in the Neuroscience of Mental Health.
Biological Psychiatry Global Open Science
, 4
(2)
, Article 100283. 10.1016/j.bpsgos.2023.100283.
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Abstract
There are prominent sex/gender differences in the prevalence, expression, and life span course of mental health and neurodiverse conditions. However, the underlying sex- and gender-related mechanisms and their interactions are still not fully understood. This lack of knowledge has harmful consequences for those with mental health problems. Therefore, we set up a cocreation session in a 1-week workshop with a multidisciplinary team of 25 researchers, clinicians, and policy makers to identify the main barriers in sex and gender research in the neuroscience of mental health. Based on this work, here we provide recommendations for methodologies, translational research, and stakeholder involvement. These include guidelines for recording, reporting, analysis beyond binary groups, and open science. Improved understanding of sex- and gender-related mechanisms in neuroscience may benefit public health because this is an important step toward precision medicine and may function as an archetype for studying diversity.
| Type: | Article |
|---|---|
| Title: | Recommendations for a Better Understanding of Sex and Gender in the Neuroscience of Mental Health |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.bpsgos.2023.100283 |
| Publisher version: | http://dx.doi.org/10.1016/j.bpsgos.2023.100283 |
| Language: | English |
| Additional information: | Crown Copyright © 2023 Published by Elsevier Inc on behalf of Society of Biological Psychiatry. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
| Keywords: | Brain, Gender, Mental health, Neurodiverse conditions, Sex |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Population, Policy and Practice Dept |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10186516 |
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