UCL Discovery Stage
UCL home » Library Services » Electronic resources » UCL Discovery Stage

Carotid Plaque-RADS: A Novel Stroke Risk Classification System

Saba, L; Cau, R; Murgia, A; Nicolaides, AN; Wintermark, M; Castillo, M; Staub, D; ... Saam, T; + view all (2024) Carotid Plaque-RADS: A Novel Stroke Risk Classification System. JACC: Cardiovascular Imaging , 17 (1) pp. 62-75. 10.1016/j.jcmg.2023.09.005.

[thumbnail of Brown_Manuscript merged clean.pdf] Text
Brown_Manuscript merged clean.pdf
Access restricted to UCL open access staff until 3 January 2025.

Download (634kB)

Abstract

Background: Carotid artery atherosclerosis is highly prevalent in the general population and is a well-established risk factor for acute ischemic stroke. Although the morphological characteristics of vulnerable plaques are well recognized, there is a lack of consensus in reporting and interpreting carotid plaque features. Objectives: The aim of this document is to establish a consistent and comprehensive approach for imaging and reporting carotid plaque by introducing the Plaque–Reporting and Data System (RADS) score. Methods: A panel of experts recognized the necessity to develop a classification system for carotid plaque and its defining characteristics. Using a multimodality analysis approach, the Plaque-RADS categories were established through consensus, drawing on existing published reports. Results: The authors present a universal classification that is applicable to both researchers and clinicians. The Plaque-RADS score offers a morphological assessment in addition to the prevailing quantitative parameter of “stenosis.” The Plaque-RADS score spans from grade 1 (indicating complete absence of plaque) to grade 4 (representing complicated plaque). Accompanying visual examples are included to facilitate a clear understanding of the Plaque-RADS categories. Conclusions: Plaque-RADS is a standardized and reliable system of reporting carotid plaque composition and morphology via different imaging modalities, such as ultrasound, computed tomography, and magnetic resonance imaging. This scoring system has the potential to help in the precise identification of patients who may benefit from exclusive medical intervention and those who require alternative treatments, thereby enhancing patient care. A standardized lexicon and structured reporting promise to enhance communication between radiologists, referring clinicians, and scientists.

Type: Article
Title: Carotid Plaque-RADS: A Novel Stroke Risk Classification System
Location: United States
DOI: 10.1016/j.jcmg.2023.09.005
Publisher version: http://dx.doi.org/10.1016/j.jcmg.2023.09.005
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: atherosclerosis, carotid plaque, carotid stenosis, complicated plaque, plaque imaging, Plaque-RADS, reporting and data system, stroke
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Brain Repair and Rehabilitation
URI: https://discovery-pp.ucl.ac.uk/id/eprint/10188849
Downloads since deposit
76Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item