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The mechanics of congenital heart disease: from a morphological trait to the functional echocardiographic evaluation

Avesani, Martina; Sabatino, Jolanda; Borrelli, Nunzia; Cattapan, Irene; Leo, Isabella; Pelaia, Giulia; Moscatelli, Sara; ... Di Salvo, Giovanni; + view all (2024) The mechanics of congenital heart disease: from a morphological trait to the functional echocardiographic evaluation. Frontiers in Cardiovascular Medicine , 11 , Article 1301116. 10.3389/fcvm.2024.1301116. Green open access

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Abstract

Advances in pediatric cardiac surgery have resulted in a recent growing epidemic of children and young adults with congenital heart diseases (CHDs). In these patients, congenital defects themselves, surgical operations and remaining lesions may alter cardiac anatomy and impact the mechanical performance of both ventricles. Cardiac function significantly influences outcomes in CHDs, necessitating regular patient follow-up to detect clinical changes and relevant risk factors. Echocardiography remains the primary imaging method for CHDs, but clinicians must understand patients' unique anatomies as different CHDs exhibit distinct anatomical characteristics affecting cardiac mechanics. Additionally, the use of myocardial deformation imaging and 3D echocardiography has gained popularity for enhanced assessment of cardiac function and anatomy. This paper discusses the role of echocardiography in evaluating cardiac mechanics in most significant CHDs, particularly its ability to accommodate and interpret the inherent anatomical substrate in these conditions.

Type: Article
Title: The mechanics of congenital heart disease: from a morphological trait to the functional echocardiographic evaluation
Open access status: An open access version is available from UCL Discovery
DOI: 10.3389/fcvm.2024.1301116
Publisher version: http://dx.doi.org/10.3389/fcvm.2024.1301116
Language: English
Additional information: This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third-party material in this article are included in the Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
Keywords: Science & Technology, Life Sciences & Biomedicine, Cardiac & Cardiovascular Systems, Cardiovascular System & Cardiology, cardiac mechanics, congenital heart diseases, advanced echocardiography, speckle tracking, three-dimensional echocardiography, ARTERIAL SWITCH OPERATION, SPECKLE-TRACKING ECHOCARDIOGRAPHY, SYSTEMIC RIGHT VENTRICLE, CARDIAC MAGNETIC-RESONANCE, GLOBAL LONGITUDINAL STRAIN, GREAT-ARTERIES, PERCUTANEOUS CLOSURE, COMPLETE TRANSPOSITION, REPAIRED TETRALOGY, SYSTOLIC FUNCTION
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science
URI: https://discovery-pp.ucl.ac.uk/id/eprint/10191744
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