van Der Louw, Elles;
Trimmel-Schwahofer, Petra;
Devlin, Anita;
Armeno, Marisa;
Thompson, Lindsey;
Cross, J Helen;
Auvin, Stephane;
(2024)
Human milk and breastfeeding during ketogenic diet therapy in infants with epilepsy: Clinical practice guideline.
Developmental Medicine & Child Neurology
10.1111/dmcn.15928.
(In press).
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Abstract
Ketogenic diet therapy (KDT) is a safe and effective treatment for epilepsy and glucose transporter type 1 (GLUT1) deficiency syndrome in infancy. Complete weaning from breastfeeding is not required to implement KDT; however, breastfeeding remains uncommon. Barriers include feasibility concerns and lack of referrals to expert centres. Therefore, practical strategies are needed to help mothers and professionals overcome these barriers and facilitate the inclusion of breastfeeding and human milk during KDT. A multidisciplinary expert panel met online to address clinical concerns, systematically reviewed the literature, and conducted two international surveys to develop an expert consensus of practical recommendations for including human milk and breastfeeding in KDT. The need to educate about the nutritional benefits of human milk and to increase breastfeeding rates is emphasized. Prospective real-world registries could help to collect data on the implementation of breastfeeding and the use of human milk in KDT, while systematically including non-seizure-related outcomes, such as quality of life, and social and emotional well-being, which could improve outcomes for infants and mothers.
| Type: | Article |
|---|---|
| Title: | Human milk and breastfeeding during ketogenic diet therapy in infants with epilepsy: Clinical practice guideline |
| Location: | England |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1111/dmcn.15928 |
| Publisher version: | http://dx.doi.org/10.1111/dmcn.15928 |
| Language: | English |
| Additional information: | © 2024 The Authors. Developmental Medicine & Child Neurology published by John Wiley & Sons Ltd on behalf of Mac Keith Press. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |
| Keywords: | Science & Technology, Life Sciences & Biomedicine, Clinical Neurology, Pediatrics, Neurosciences & Neurology, NEUROPSYCHOLOGICAL DEVELOPMENT, HINDMILK, BENEFITS, MOTHERS, PHENYLKETONURIA, UROLITHIASIS, EXPERIENCE, SPASMS, COHORT, BORN |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > ICH - Directors Office |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10191779 |
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