Kambanis, P Evelyna;
Tabri, Nassim;
McPherson, Iman;
Gydus, Julia E;
Kuhnle, Megan;
Stern, Casey M;
Asanza, Elisa;
... Thomas, Jennifer J; + view all
(2024)
Prospective Two-Year Course and Predictors of Outcome in Avoidant/Restrictive Food Intake Disorder.
Journal of the American Academy of Child & Adolescent Psychiatry
10.1016/j.jaac.2024.04.010.
(In press).
Text
1-s2.0-S0890856724002387-main.pdf - Accepted Version Access restricted to UCL open access staff until 7 May 2025. Download (2MB) |
Abstract
Objective: To evaluate the 2-year course and outcomes of full and subthreshold avoidant/restrictive food intake disorder (ARFID) in youth ages 9-23 at baseline using a prospective longitudinal design to characterize the remission and persistence of ARFID, evaluate diagnostic crossover, and identify predictors of outcome. We hypothesized that greater severity in each ARFID profile – sensory sensitivity, fear of aversive consequences, and lack of interest – would predict greater likelihood of illness persistence, controlling for age, sex, BMI percentile, ARFID treatment status, and baseline diagnosis. // Method: We followed participants (N = 100; ages 9-23 years; 49% female, 91% White) over two years. We used the Pica, ARFID, and Rumination Disorder Interview across three time points (Baseline, Year 1, Year 2) to measure the severity of each ARFID profile and evaluate illness persistence or remission, and the Eating Disorder Assessment for DSM-5 to evaluate diagnostic crossover. // Results: Across the 2-year follow-up period, half the sample persisted with their original diagnosis, and 3% of participants experienced diagnostic shift to anorexia nervosa. Greater severity in the sensory sensitivity and lack of interest profiles was associated with higher likelihood of ARFID persistence at Year 1 only; greater severity in the fear of aversive consequences profile was associated with higher likelihood of ARFID remission at Year 2 only. // Conclusion: Findings underscore the distinctiveness of ARFID from other eating disorders and emphasize its persistence over 2 years. Results also highlight the predictive validity and prognostic value of ARFID profiles (i.e., sensory sensitivity, fear of aversive consequences, lack of interest).
Type: | Article |
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Title: | Prospective Two-Year Course and Predictors of Outcome in Avoidant/Restrictive Food Intake Disorder |
Location: | United States |
DOI: | 10.1016/j.jaac.2024.04.010 |
Publisher version: | http://dx.doi.org/10.1016/j.jaac.2024.04.010 |
Language: | English |
Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
Keywords: | Avoidant/restrictive food intake disorder; ARFID; feeding and eating disorders; longitudinal study; longitudinal course |
UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Population, Policy and Practice Dept |
URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10192384 |
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