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Non-pharmacological interventions in the management of dementia-related psychosis: a systematic review and meta-analysis

Burnand, Alice; Rookes, Tasmin; Davies, Nathan; Mahmood, Farah; Walters, Kate; Orleans Foli, Stephen; Sajid, Madiha; ... Frost, Rachael; + view all (2024) Non-pharmacological interventions in the management of dementia-related psychosis: a systematic review and meta-analysis. International Journal of Geriatric Psychiatry , 39 (8) , Article e6129. 10.1002/gps.6129. Green open access

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Abstract

OBJECTIVE: As populations age globally, there is an increasing prevalence of dementia, with an estimated 153 million living with dementia by 2050. Up to 70% of people with dementia experience dementia-related psychosis (D-RP). Antipsychotic medications are associated with many adverse effects in older people. This review aims to evaluate the evidence of non-pharmacological interventions in managing D-RP. METHOD: The search of Medline, EMBASE, Web of Science, CINAHL, PsycINFO, and Cochrane included randomised controlled trials that evaluated non-pharmacological interventions. Data extraction and assessment of quality were assessed independently by two researchers. Heterogenous interventions were pooled using meta-analysis. RESULTS: A total of 18 articles (n = 2040 participants) were included and categorised into: sensory-, activity-, cognitive- and multi-component-orientated. Meta-analyses showed no significant impact in reducing hallucinations or delusions but person-centred care, cognitive rehabilitation, music therapy, and robot pets showed promise in single studies. CONCLUSIONS AND IMPLICATIONS: Future interventions should be developed and evaluated with a specific focus on D-RP as this was not the aim for many of the included articles.

Type: Article
Title: Non-pharmacological interventions in the management of dementia-related psychosis: a systematic review and meta-analysis
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1002/gps.6129
Publisher version: https://doi.org/10.1002/gps.6129
Language: English
Additional information: © 2024 The Author(s). International Journal of Geriatric Psychiatry published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Keywords: Care home, delusions, dementia, hallucinations, interventions, non‐pharmacological, nursing home, psychosis, Humans, Dementia, Psychotic Disorders, Music Therapy
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Primary Care and Population Health
URI: https://discovery-pp.ucl.ac.uk/id/eprint/10195589
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