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Why selective screening for asymptomatic carotid stenosis is currently appropriate: a special report

Paraskevas, Kosmas I; Dardik, Alan; Schermerhorn, Marc L; Liapis, Christos D; Mansilha, Armando; Lal, Brajesh K; Gray, William A; ... AbuRahma, Ali F; + view all (2024) Why selective screening for asymptomatic carotid stenosis is currently appropriate: a special report. Expert Review of Cardiovascular Therapy , 22 (4-5) pp. 159-165. 10.1080/14779072.2024.2330660. Green open access

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Abstract

Introduction: Two of the main reasons recent guidelines do not recommend routine population-wide screening programs for asymptomatic carotid artery stenosis (AsxCS) is that screening could lead to an increase of carotid revascularization procedures and that such mass screening programs may not be cost-effective. Nevertheless, selective screening for AsxCS could have several benefits. This article presents the rationale for such a program. // Areas covered: The benefits of selective screening for AsxCS include early recognition of AsxCS allowing timely initiation of preventive measures to reduce future myocardial infarction (MI), stroke, cardiac death and cardiovascular (CV) event rates. // Expert Opinion: Mass screening programs for AsxCS are neither clinically effective nor cost-effective. Nevertheless, targeted screening of populations at high risk for AsxCS provides an opportunity to identify these individuals earlier rather than later and to initiate a number of lifestyle measures, risk factor modifications, and intensive medical therapy in order to prevent future strokes and CV events. For patients at ‘higher risk of stroke’ on best medical treatment, a prophylactic carotid intervention may be considered.

Type: Article
Title: Why selective screening for asymptomatic carotid stenosis is currently appropriate: a special report
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1080/14779072.2024.2330660
Publisher version: http://dx.doi.org/10.1080/14779072.2024.2330660
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Asymptomatic carotid atherosclerosis; carotid plaque burden; carotid stenosis; guidelines; screening; stroke
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
URI: https://discovery-pp.ucl.ac.uk/id/eprint/10195813
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