Ueda-Consolvo, T;
Ishida, M;
Nakamura, T;
Yanagisawa, S;
Tsuboi, K;
Wakabayashi, T;
Hayashi, A;
... Zinkernage, MS; + view all
(2024)
Biosimilar ranibizumab (BS1) – early experience from Japan (BRIJ study).
Eye
, 38
pp. 3193-3196.
10.1038/s41433-024-03220-z.
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Abstract
Anti-vascular endothelial growth factor (VEGF) injections are the mainstay of treatment for retinal vascular diseases. However, despite their efficacy, the cost of long term intravitreal injections poses a significant burden on patients and healthcare systems. Recently, ranibizumab biosimilar (ranibizumab BS1, Senju Pharmaceuticals Co Ltd) has become available in Japan [1]. Ranibizumab BS1 is expected to have equivalent efficacy to the originator ranibizumab (0.5 mg) (Lucentis, Genentech, USA) but costs approximately 50% less (85,535 yen/560 USD versus 166,698 yen/1090 USD at the time of approval) per injection. Here, we report the early clinical outcomes regarding safety and efficacy in patients receiving ranibizumab BS1 injections for various retinal diseases. This study is part of the initiative undertaken by the international retina biosimilar study group (Inter BIOS Group).
| Type: | Article |
|---|---|
| Title: | Biosimilar ranibizumab (BS1) – early experience from Japan (BRIJ study) |
| Location: | England |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1038/s41433-024-03220-z |
| Publisher version: | http://dx.doi.org/10.1038/s41433-024-03220-z |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | Biologics, Pharmacology |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Ophthalmology |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10196360 |
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