Mehta, Gautam;
Jalan, Rajiv;
(2025)
Pyroptosis in Liver Failure: A Twisted Firestarter.
Journal of Hepatology
10.1016/j.jhep.2024.08.023.
(In press).
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Abstract
We read with great interest the review article by Taru and colleagues, focusing on the role of inflammasomes in chronic liver disease.1 The authors have produced a thorough outline of inflammasome biology as well as an overview of potential therapeutic strategies in liver disease. We would like to contribute additional perspectives regarding pyroptosis-directed therapies in decompensated cirrhosis and acute-on-chronic liver failure (ACLF).
| Type: | Article |
|---|---|
| Title: | Pyroptosis in Liver Failure: A Twisted Firestarter |
| Location: | Netherlands |
| DOI: | 10.1016/j.jhep.2024.08.023 |
| Publisher version: | https://doi.org/10.1016/j.jhep.2024.08.023 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | acute-on-chronic liver failure, cirrhosis, inflammasome, pyroptosis |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Inst for Liver and Digestive Hlth |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10196653 |
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