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What over the counter (OTC) products have been evaluated for anxiety in adults aged 18–60? A scoping review

Mathew, Silvy; (2024) What over the counter (OTC) products have been evaluated for anxiety in adults aged 18–60? A scoping review. Journal of Mental Health 10.1080/09638237.2024.2408231. (In press). Green open access

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Abstract

Background Anxiety symptoms and disorders are common in the UK. Whilst waiting for, or alongside, treatments such as anxiolytics or psychological therapies, people often self-manage anxiety symptoms with products purchased over-the-counter (OTC), such as herbal medicines or dietary supplements. However, the evidence for these products is often presented across different reviews and is not easy for patients or healthcare professionals to compare and understand. Aims To determine the nature and size of the evidence base available for these products. Methods A scoping review. CENTRAL, MEDLINE, EMBASE, PsycInfo, and AMED (inception—Dec 2022) were searched for RCTs assessing OTC products in people aged 18–60 with symptoms or a diagnosis of anxiety. Results In total 69 papers assessing a range of products were found, which mostly focussed on kava, lavender, saffron, probiotics, Galphimia glauca and valerian. Studies used varying dosages. Compared to herbal medicine studies, there were much fewer dietary supplement studies and homeopathic remedy studies, despite some of use of these by the general public. Conclusion Future research needs to investigate commonly used but less evaluated products (e.g. chamomile, St John’s Wort) and to evaluate products against or alongside conventional treatments to better reflect patient decision making.

Type: Article
Title: What over the counter (OTC) products have been evaluated for anxiety in adults aged 18–60? A scoping review
Open access status: An open access version is available from UCL Discovery
DOI: 10.1080/09638237.2024.2408231
Publisher version: https://www.tandfonline.com/doi/full/10.1080/09638...
Language: English
Additional information: This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third-party material in this article are included in the Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
Keywords: Anxiety; herbal medicine; homeopathy; dietary supplements; over-the-counter
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Education
UCL > Provost and Vice Provost Offices > School of Education > UCL Institute of Education
UCL > Provost and Vice Provost Offices > School of Education > UCL Institute of Education > IOE - Social Research Institute
URI: https://discovery-pp.ucl.ac.uk/id/eprint/10197986
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